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In the 1972 examine "The Apportionment of Human Range", Richard Lewontin carried out a fixation index (FST) statistical analysis using 17 markers, together with blood group proteins, from people across classically outlined "races" (Caucasian, African, Mongoloid, South Asian Aborigines, Amerinds, Oceanians, and Australian Aborigines). Once they analysed three geographically distinct populations (European, African, and East Asian) and measured genetic similarity over many 1000's of loci, the reply to their query was "never"; nevertheless, measuring similarity utilizing smaller numbers of loci yielded substantial overlap between these populations. Witherspoon et al. try and reply the question "How usually is a pair of people from one population genetically extra dissimilar than two people chosen from two totally different populations?" The answer is determined by the variety of polymorphisms used to outline that dissimilarity, and the populations being in contrast. Or in different phrases, the frequency of the alleles tends to cluster otherwise for different populations. These relationships might be extracted using commonly used ordination and cluster evaluation techniques.
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