Quetiapine Fumarate 50mg Tablet typically begins to exert its effects within 1 to 2 hours after oral administration, reaching peak plasma concentrations during this period. However, noticeable improvements in symptoms may take several days to weeks, depending on the condition being treated. For mood disorders, some individuals may observe benefits within 1 to 2 weeks, but achieving the full therapeutic effect often requires 4 to 6 weeks of consistent use. It's crucial to adhere to your prescribed regimen and consult your healthcare provider before making any changes to your medication.